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Diterpenoids from the Roots of Salvia yunnanensis |
| Fan Xia1, Chun-Yan Wu2, Xing-Wei Yang2, Xian Li1, Gang Xu2 |
1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming 650500, People's Republic of China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China |
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Abstract Two new diterpenoids, salyunnanins I and J(1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities.
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| Keywords
Salvia yunnanensis
Diterpenoid
Cytotoxicity
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| Fund:The work was financially supported by the National Natural Sciences Foundation of China(81373291), the National Science and Technology Support Program of China(2013BAI11B02), and the foundation from Chinese Academy of Sciences to Dr G. Xu. |
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Issue Date: 11 February 2018
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