Characterization of New <i>Ent</i>-kaurane Diterpenoids of Yunnan Arabica Coffee Beans

doi:10.1007/s13659-016-0099-1

Natural Products and Bioprospecting

2016, Vol. 6

Issue (4) : 217-223 DOI: 10.1007/s13659-016-0099-1

Original article

Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans

Rui Chu^1,2, Luo-Sheng Wan¹, Xing-Rong Peng¹, Mu-Yuan Yu^1,2, Zhi-Run Zhang¹, Lin Zhou¹, Zhong-Rong Li¹, Ming-Hua Qiu^1,2

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China

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Abstract Five new ent-kaurane diterpenoids, named mascaroside III-V (1-3), and 20-nor-cofaryloside I-II (4-5), together with seven known diterpenoids, were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee. Their chemical structures were elucidated by extensive spectroscopic analyses. Meanwhile, cytotoxicity assay against HL-60, A-549, SMMC-7721, MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity.

Keywords Coffea arabica L. Green coffee beans Diterpenoids Structural elucidation

Fund:This work was supported financially by Programme of Key New Productions of Yunnan Province,Centre of CHINA (No.2015BB002);The STS Programme of Chinese Academy of Sciences (KFJ-SW-STS-143-8);as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2015-ZZ09)

Issue Date: 08 February 2018

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	Rui Chu
	Luo-Sheng Wan
	Xing-Rong Peng
	Mu-Yuan Yu
	Zhi-Run Zhang
	Lin Zhou
	Zhong-Rong Li
	Ming-Hua Qiu

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Rui Chu,Luo-Sheng Wan,Xing-Rong Peng, et al. Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans[J]. Natural Products and Bioprospecting, 2016, 6(4): 217-223.

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http://npb.kib.ac.cn/EN/10.1007/s13659-016-0099-1 OR http://npb.kib.ac.cn/EN/Y2016/V6/I4/217

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