Natural Products and Bioprospecting    2018, Vol. 8 Issue (1) : 31-35     DOI: 10.1007/s13659-017-0146-6
ORIGINAL ARTICLES |
Anemhupehins A-C, Podocarpane Diterpenoids from Anemone hupehensis
Xing Yu, Kai-Ting Duan, Zhen-Xiong Wang, He-Ping Chen, Xiao-Qing Gan, Rong Huang, Zheng-Hui Li, Tao Feng, Ji-Kai Liu
School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
Download: PDF(3618 KB)   HTML ()  
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks    
Abstract  Three new podocarpane diterpenoids, namely anemhupehins A-C (1-3), together with four known analogues (4-7), have been isolated from aerial parts of Anemone hupehensis. Their structures were characterized based on extensive spectroscopic data. Compounds 1 and 4 showed certain cytotoxicities against human cancer cell lines.
Keywords Anemone hupehensis      Podocarpane diterpenoids      Cytotoxicity     
Corresponding Authors: Tao Feng, Ji-Kai Liu     E-mail: tfeng@mail.scuec.edu.cn;jkliu@mail.kib.ac.cn
Issue Date: 27 February 2018
Service
E-mail this article
E-mail Alert
RSS
Articles by authors
Xing Yu
Kai-Ting Duan
Zhen-Xiong Wang
He-Ping Chen
Xiao-Qing Gan
Rong Huang
Zheng-Hui Li
Tao Feng
Ji-Kai Liu
Trendmd:   
Cite this article:   
Xing Yu,Kai-Ting Duan,Zhen-Xiong Wang, et al. Anemhupehins A-C, Podocarpane Diterpenoids from Anemone hupehensis[J]. Natural Products and Bioprospecting, 2018, 8(1): 31-35.
URL:  
http://npb.kib.ac.cn/EN/10.1007/s13659-017-0146-6     OR     http://npb.kib.ac.cn/EN/Y2018/V8/I1/31
1. P.L. Majumder, D.C. Maiti, W. Kraus, M. Bokel, Phytochemistry 26, 3021-3023 (1987)
2. I. Ara, B.S. Siddiqui, S. Faigi, S. Siddiqui, Phytochemistry 27, 1801-1804 (1988)
3. S. Siddiqui, I. Ara, S. Faigi, T. Mahmood, B.S. Siddiqui, Phytochemistry 27, 3903-3907 (1988)
4. I. Ara, B.S. Siddiqui, S. Faigi, S. Siddiqui, J. Nat. Prod. 51, 1054-1061 (1988)
5. I. Ara, B.S. Siddiqui, S. Faigi, S. Siddiqui, J. Nat. Prod. 20, 816-820 (1990)
6. M.D. Zoghbl, N.F. Roque, H.E. Gottlieb, Phytochemistry 20, 1669-1673 (1981)
7. M.A.D. Alvarenga, J.D. Silva, H.E. Gottlieb, O.R. Gottlieb, Phytochemistry 20, 1159-1163 (1981)
8. R.C. Cambie, L.M. Mander, Tetrahedron 18, 465-475 (1962)
9. R.A. Franich, P.D. Gadgil, L. Shain, Physiol. Plant. Pathol. 23, 183-195 (1983)
10. H.T. Cheung, T. Miyase, M.P. Lenguyen, M.A. Smal, Tetrahedron 49, 7903-7915 (1993)
11. T. Oishi, Y. Otsuka, T. Limori, Y. Sawada, S. Ochi, Patent JP 91-36296 (1992)
12. M. Wang, F. Wu, Y. Chen, Phytochemistry 34, 1395-1397 (1993)
13. M.K. Wang, F.E. Wu, Y.Z. Chen, Phytochemistry 44, 333-335 (1996)
14. A. Yokosuka, T. Sano, K. Hashimoto, H. Sakagami, Y. Mimaki, Chem. Pharm. Bull. 57, 1425-1430 (2009)
15. F. Li, X. Liu, M. Tang, B. Chen, L. Ding, L. Chen, M. Wang, Carbohydr. Res. 353, 49-56 (2012)
16. G.B. Evans, R.H. Furneaux, M.B. Gravestock, G.P. Lynch, G.K. Scott, Bioorg. Med. Chem. 7, 1953-1964 (1999)
17. Y.H. Kuo, C.I. Chang, C.K. Lee, Chem. Pharm. Bull. 48, 597-599 (2000)
18. C.T.A. Minh, N.M. Khoi, P.T. Thuong, I.H. Hwang, D.W. Kim, M.K. Na, Biochem. Syst. Ecol. 44, 270-274 (2012)
19. T.J. Mosmann, J. Immunol. Methods 65, 55-63 (1983)
[1] Xin Wei, Afsar Khan, Da Song, Zhi Dai, Ya-Ping Liu, Hao-Fei Yu, Bei Wang, Pei-Feng Zhu, Cai-Feng Ding, Xu-Dong Zhao, Yi-Fen Wang, Xiao-Dong Luo. Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan[J]. Natural Products and Bioprospecting, 2017, 7(4): 323-327.
[2] Xu-Jie Qin, Tong Shu, Qian Yu, Huan Yan, Wei Ni, Lin-Kun An, Pan-Pan Li, Yin-E Zhi, Afsar Khan, Hai-Yang Liu. Cytotoxic Acylphloroglucinol Derivatives from Callistemon salignus[J]. Natural Products and Bioprospecting, 2017, 7(4): 315-321.
[3] Miao Liu, Zheng-Xi Hu, Yuan-Qing Luo, Min Zhou, Wei-Guang Wang, Xiao-Nian Li, Xue Du, Jian-Xin Pu, Han-Dong Sun. Two New Compounds from Schisandra propinqua var. propinqua[J]. Natural Products and Bioprospecting, 2017, 7(3): 257-262.
[4] Li-Xia Wang, Hai-Rong Zheng, Fu-Cai Ren, Tian-Ge Chen, Xiang-Mei Li, Xian-Jun Jiang, Fei Wang. Polysubstituted Isoflavonoids from Spatholobus suberectus, Flemingia macrophylla, and Cudrania cochinchinensis[J]. Natural Products and Bioprospecting, 2017, 7(2): 201-206.
[5] Satheesh Kumar Palanisamy, N. M. Rajendran, Angela Marino. Natural Products Diversity of Marine Ascidians (Tunicates; Ascidiacea) and Successful Drugs in Clinical Development[J]. Natural Products and Bioprospecting, 2017, 7(1): 1-111.
[6] Mehtab Parveen, Faheem Ahmad, Ali Mohammed Malla, Shaista Azaz, Mahboob Alam, Omer A. Basudan, Manuela Ramos Silva, Pedro S. Pereira Silva. Acetylcholinesterase and Cytotoxic Activity of Chemical Constituents of Clutia lanceolata Leaves and its Molecular Docking Study[J]. Natural Products and Bioprospecting, 2016, 6(6): 267-278.
[7] Qian-Qian Meng, Xing-Rong Peng, Shuang-Yang Lu, Luo-Sheng Wan, Xia Wang, Jin-Run Dong, Rui Chu, Lin Zhou, Xiao-Nian Li, Ming-Hua Qiu. Lactam Triterpenoids from the Bark of Toona sinensis[J]. Natural Products and Bioprospecting, 2016, 6(5): 239-245.
[8] Xiang-Mei Li, Xian-Jun Jiang, Ku Yang, Li-Xia Wang, Shi-Zhen Wen, Fei Wang. Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata[J]. Natural Products and Bioprospecting, 2016, 6(5): 233-237.
[9] Vincent E. Rasamison, Peggy J. Brodie, Emilio F. Merino, Maria B. Cassera, Michel A. Ratsimbason, Stephan Rakotonandrasana, Andriamalala Rakotondrafara, Elie Rafidinarivo, David G. I. Kingston, Harinantenaina L. Rakotondraibe. Furoquinoline Alkaloids and Methoxyflavones from the Stem Bark of Melicope madagascariensis (Baker) T. G. Hartley[J]. Natural Products and Bioprospecting, 2016, 6(5): 261-265.
[10] Ling Ni, Xiu-Hong Zhong, Jie Cai, Mei-Fen Bao, Bing-Jie Zhang, Jing Wu, Xiang-Hai Cai. Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina[J]. Natural Products and Bioprospecting, 2016, 6(3): 149-154.
[11] Christian Bäcker, Malgorzata N. Drwal, Robert Preissner, Ulrike Lindequist. Inhibition of DNA-Topoisomerase I by Acylated Triterpene Saponins from Pittosporum angustifolium Lodd[J]. Natural Products and Bioprospecting, 2016, 6(2): 141-147.
[12] Fan Xia,Chun-Yan Wu,Xing-Wei Yang, Xian Li,Gang Xu. Diterpenoids from the Roots of Salvia yunnanensis[J]. Natural Products and Bioprospecting, 2015, 5(6): 307-312.
[13] Tao Feng, Juan He, Hong-Lian Ai, Rong Huang, Zheng-Hui Li, Ji-Kai Liu. Three New Triterpenoids from European Mushroom Tricholoma terreum[J]. Natural Products and Bioprospecting, 2015, 5(4): 205-208.
[14] Da-Song Yang, Shuang-Mei Wang, Wei-Bing Peng, Yong-Ping Yang, Ke-Chun Liu, Xiao-Li Li, Wei-Lie Xiao. Minor Prenylated Flavonoids from the Twigs of Macaranga adenantha and Their Cytotoxic Activity[J]. Natural Products and Bioprospecting, 2015, 5(2): 105-109.
[15] Rong-Hua Yin, Zhen-Zhu Zhao, Xu Ji, Ze-Jun Dong, Zheng-Hui Li, Tao Feng, Ji-Kai Liu. Steroids and Sesquiterpenes From Cultures of the Fungus Phellinus igniarius[J]. Natural Products and Bioprospecting, 2015, 5(1): 17-22.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed