|
|
|
|
|
|
New Diterpenoids from Clerodendranthus spicatus |
Ya-Mei Li1,2, Bing Xiang1, Xiao-Zheng Li1,2, Yong-Ming Yan2, Yong-Xian Cheng1,2 |
1. Yunnan University of Traditional Chinese Medicine, Kunming 650504, People's Republic of China; 2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China |
|
|
Abstract Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 lM.
|
Keywords
Clerodendranthus spicatus
Diterpenoid
Neoorthosiphonones B and C
|
Fund:This study was financially supported by grants from Center of Cooperative Innovation for South China Medicine of Yunnan Province and National Science Fund for Distinguished Young Scholars (81525026). |
Issue Date: 06 February 2018
|
|
|
1. Y.L. Chen, C.H. Tan, J.J. Tan, X.M. Zhao, S.H. Jiang, D.Y. Zhu, Nat. Prod. Res. Dev. 21, 885-891 (2009) 2. Z. Chen, C.X. Yang, X.J. Mao, Pharm. Inf. 4, 23-30 (2015) 3. M.A. Hossain, S.M.M. Rahman, Arab. J. Chem. 8, 218-221 (2015) 4. S.C. Guan, G.Y. Fan, Helv. Chim. Acta 97, 1708-1713 (2014) 5. Y.L. Chen, C.H. Tan, J.J. Tan, X.M. Zhao, S.H. Jiang, D.Y. Zhu, Helv. Chim. Acta 92, 2802-2807 (2009) 6. X.X. Di, S.Q. Wang, X.L. Zhang, B. Wang, H.X. Lou, X.N. Wang, Phytochem. Lett. 6, 412-417 (2013) 7. H.C. Zhou, L. Yang, R.Z. Guo, J. Li, J. Asian Nat. Prod. Res. (2016). doi:10.1080/10286020.2016.1277707 8. Z.C. Sun, Q.X. Zheng, G.X. Ma, X.P. Zhang, J.Q. Yuan, H.F. Wu, H.L. Liu, J.S. Yang, X.D. Xu, Phytochem. Lett. 8, 16-21 (2014) 9. G.X. Ma, X.P. Zhang, P.F. Li, Z.H. Sun, N.L. Zhu, Y.D. Zhu, J.S. Yang, D.L. Chen, H.F. Wu, X.D. Xu, Fitoterapia 105, 61-65 (2015) 10. Q. Li, Y.N. He, X.W. Shi, L.Y. Kang, L.Y. Niu, X.G. Wang, W. Feng, Fitoterapia 114, 110-114 (2016) 11. X.Z. Li, Y.M. Yan, Y.X. Cheng, Nat. Prod. Res. Dev. 29, 183-189 (2017) 12. S. Awale, Y. Tezuka, M. Kobayashi, J.Y. Ueda, S. Kadota, Tetrahedron Lett. 45, 1359-1362 (2004) 13. L. Dong, Q. Luo, L.Z. Cheng, Y.M. Yan, Y.X. Cheng, S.M. Wang, Fitoterapia 117, 147-153 (2017) |
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|