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Indole Glycosides from Aqueous Fraction of Strychnos nitida |
| Bei Wang1,2, Zhi Dai3, Lu Liu1,2, Xin Wei1,2, Pei-Feng Zhu2, Hao-Fei Yu1,2, Ya-Ping Liu1,4, Xiao-Dong Luo1,4 |
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming 650201, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3. Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of sciences, Kunming 650223, Yunnan, China;
4. Yunnan Key Laboratory of Natural Medicinal Chemistry, Chinese Academy of Sciences, Kunming 650201, China |
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Abstract Three new indole glycosides 22-deoxystrictosamide (1), 22-deoxystrictosamide Nb-oxide (2) and vincosamide 2'-O-β-D-xylopyranoside-11-O-β-D-glucopyranoside (3), together with four known analogues were isolated from aqueous fraction of Strychnos nitida. Their structures were elucidated on the basis of extensive analysis of spectroscopic data. All the alkaloids were tested for their cytotoxic activity, but they did not show any exciting result.
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| Keywords
Strychnos nitida
Indole glycosides
Alkaloids
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| Fund:This project was financially supported by the National Natural Science Foundation of China (81225024);We also thank the analytical group of the Laboratory of Phytochemistry,Kunming Institute of Botany for spectral measurements |
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Issue Date: 31 January 2018
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