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Natural-derived acetophenones: chemistry and pharmacological activities |
| Hamid Ahmadpourmir1, Homayoun Attar1, Javad Asili1, Vahid Soheili2, Seyedeh Faezeh Taghizadeh1, Abolfazl Shakeri1 |
1. Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;
2. Department of Pharmaceutical Control, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran |
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Abstract Acetophenones are naturally occurring phenolic compounds which have found in over 24 plant families and also fungi strains. They are exist in both free or glycosides form in nature. The biological activities of these compounds have been assayed and reported including cytotoxicity, antimicrobial, antimalarial, antioxidant and antityrosinase activities. Herein, we review the chemistry and biological activity of natural acetophenone derivatives that have been isolated and identified until January 2024. Taken together, it was reported 252 acetophenone derivatives in which the genera Melicope (69) and Acronychia (44) were the principal species as producers of acetophenones.
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Acetophenones
Bioactivity
Melicope
Phytochemicals
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Corresponding Authors:
Abolfazl Shakeri,E-mail:plantchem87@gmail.com,shakeria@mums.ac.ir
E-mail: plantchem87@gmail.com,shakeria@mums.ac.ir
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Issue Date: 01 August 2024
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