New Diterpenoids from <i>Clerodendranthus spicatus</i>

doi:10.1007/s13659-017-0128-8

Natural Products and Bioprospecting

2017, Vol. 7

Issue (3) : 263-267 DOI: 10.1007/s13659-017-0128-8

New Diterpenoids from Clerodendranthus spicatus

Ya-Mei Li^1,2, Bing Xiang¹, Xiao-Zheng Li^1,2, Yong-Ming Yan², Yong-Xian Cheng^1,2

1. Yunnan University of Traditional Chinese Medicine, Kunming 650504, People's Republic of China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

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Abstract Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 lM.

Keywords Clerodendranthus spicatus Diterpenoid Neoorthosiphonones B and C

Fund:This study was financially supported by grants from Center of Cooperative Innovation for South China Medicine of Yunnan Province and National Science Fund for Distinguished Young Scholars (81525026).

Issue Date: 06 February 2018

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Ya-Mei Li,Bing Xiang,Xiao-Zheng Li, et al. New Diterpenoids from Clerodendranthus spicatus[J]. Natural Products and Bioprospecting, 2017, 7(3): 263-267.

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http://npb.kib.ac.cn/EN/10.1007/s13659-017-0128-8 OR http://npb.kib.ac.cn/EN/Y2017/V7/I3/263

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