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New acetogenin katsuurallene from Laurencia saitoi collected from Katsuura, Japan |
| Yu Minamida1,8, Hiroshi Matsuura2, Takahiro Ishii3, Miyu Miyagi3, Yuto Shinjo3, Kosuke Sato4, Takashi Kamada4, Yoshihiro Mihara5, Iwao Togashi2, Keisuke Sugimoto2, Tsuyoshi Abe6, Norio Kikuchi7, Minoru Suzuki7 |
1 Advanced Course of Applied Chemistry, National Institute of Technology, Asahikawa College, Shunkodai 2-2-1-6, Asahikawa, Hokkaido 071-8142, Japan;
2 Department of Materials Chemistry, National Institute of Technology, Asahikawa Collage, Shunkodai 2-2-1-6, Asahikawa, Hokkaido 071-8142, Japan;
3 Department of Biosciences and Biotechnology, Faculty of Agriculture, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan;
4 Department of Materials and Life Science, Faculty of Science and Technology, Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555, Japan;
5 Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Maeda 7, 15-4-1, Teine-ku, Sapporo, Hokkaido 006-8590, Japan;
6 The Hokkaido University Museum, Hokkaido University, N10 W8, Kita-ku, Sapporo, Hokkaido 060-0810, Japan;
7 Coastal Branch of Natural History Museum and Institute, Chiba,, 123 Yoshio, Katsuura, Chiba 299-5242, Japan;
8 Present Address: Department of Life Science, Graduate School of Engineering Science, Akita University, 1-1 Tegatagakuen-machi, Akita 010-8502, Japan |
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Abstract We examined the chemical constitution of the red alga Laurencia saitoi Perestenko, collected from Katsuura, Boso Peninsula, Chiba Prefecture, Japan. This specimen produced a new polyhalogenated acetogenin, named katsuurallene (1), which structure was determined by the spectral methods, along with known diterpene, deoxyparguerol (2) and triterpene, thyrsiferol (3). In this paper we describe the structural elucidation of katsuurallene together with some biological activities.
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| Keywords
Laurencia
Rhodomelaceae
Acetogenin
Triterpene
Diterpene
Biological activity
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| Fund:The authors are grateful to Mr. H. Akutsu (Central Laboratory for Research and Education, Center for Advanced Research and Education, Asahikawa Medical University) for the measurement of high resolution mass spectra. This work was supported by JSPS KAKENHI Grant Numbers 18K05799 and 21K14904. |
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Corresponding Authors:
Hiroshi Matsuura, E-mail:matsuura@asahikawa-nct.ac.jp
E-mail: matsuura@asahikawa-nct.ac.jp
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Issue Date: 30 May 2022
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