New jatropholane-type diterpenes from <i>Jatropha curcas cv. Multiflorum</i> CY Yang

doi:10.1007/s13659-013-0031-x

Natural Products and Bioprospecting

2013, Vol. 3

Issue (3) : 99-102 DOI: 10.1007/s13659-013-0031-x

Regular Article

New jatropholane-type diterpenes from Jatropha curcas cv. Multiflorum CY Yang

Yuan-Feng YANG^a,b, Jie-Qing LIU^a, Lei SHI^a,c, Zhong-Rong LI^a, Ming-Hua QIU^a,b

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b University of Chinese Academy of Sciences, Beijing 100049, China;
c Yunnan Agricultural University, Kunming 650201, China

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Abstract Three new jatropholane-type diterpenoids, jatropholones C-E (1-3), along with seven other known compounds, including sikkimenoid B (4), jatrophaldehyde (5), epi-jatrophaldehyde (6), epi-jatrophol (7), jatrophol (8), jatropholone A (9), and jatropholone B (10), were isolated from the roots of a natural cultivar of Jatropha curcas (J. curcas cv. Multiflorum CY Yang). The structural elucidations of 1-3 were accomplished by extensive NMR analysis. Compounds 4, 6, and 8 demonstrated inhibition activity against the microorganisms with the MIC values from 0.10 to 0.18 mg/mL.

Keywords Jatropha curcas cv. Multiflorum Euphorbiaceae diterpenes antibacterial

Fund:The authors are sincerely grateful to Prof. Cheng-Yuan Yang of the Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, for the identification of the plant. This work was financially supported by the Key Projects of the Chinese Ministry of Science and Technology (2007BAD32B01-03 and SB2007FY400), the National Natural Science Foundation of China (81202437) and the National Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-038).

Issue Date: 11 February 2018

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Yuan-Feng YANG,Jie-Qing LIU,Lei SHI, et al. New jatropholane-type diterpenes from Jatropha curcas cv. Multiflorum CY Yang[J]. Natural Products and Bioprospecting, 2013, 3(3): 99-102.

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http://npb.kib.ac.cn/EN/10.1007/s13659-013-0031-x OR http://npb.kib.ac.cn/EN/Y2013/V3/I3/99

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