Quebrachitol: Global Status and Basic Research

doi:10.1007/s13659-017-0120-3

Natural Products and Bioprospecting

2017, Vol. 7

Issue (1) : 113-122 DOI: 10.1007/s13659-017-0120-3

Review Article

Quebrachitol: Global Status and Basic Research

Dong Wang¹, Shu-Qun Zhang¹, Zhe Chang¹, De-Xin Kong², Zhi-Li Zuo^1,3

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
2. State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China;
3. Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, China

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Abstract Recently, there has been a renewed interest in the natural-products-inspired drugs. Quebrachitol (QCT) is one of naturally occurring optically active cyclitols that has now received considerable attention. Until the last decade, it came to be a starting point for the lead discovery. In this review, we had a discussion on the basic research of QCT, including its source, structure, properties, and the recent advances on its application. The biological activities and QCT-inspired leads that are potentially effective for treating human diseases were also discussed.

Keywords Quebrachitol (QCT) Structure Biological activity Application

Fund:We gratefully thank financial assistance from the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences (Grant Number P2013-ZZ05), Fund of Basic Research Plan of Yunnan Provincial Science and Technology Department (Grant Number 2014FA042). We also appreciate the support of Western Light Talent Culture Project[2014]91(to Z. Z.).

About author: 10.1007/s13659-017-0120-3

Issue Date: 06 February 2018

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Dong Wang,Shu-Qun Zhang,Zhe Chang, et al. Quebrachitol: Global Status and Basic Research[J]. Natural Products and Bioprospecting, 2017, 7(1): 113-122.

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http://npb.kib.ac.cn/EN/10.1007/s13659-017-0120-3 OR http://npb.kib.ac.cn/EN/Y2017/V7/I1/113

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