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The Chemistry and Biological Activities of Natural Products from Northern African Plant Families: From Taccaceae to Zygophyllaceae |
| Fidele Ntie-Kang1,2, Leonel E. Njume3, Yvette I. Malange2, Stefan Günther4, Wolfgang Sippl1, Joseph N. Yong2 |
1. Department of Pharmaceutical Chemistry, Martin-Luther University of Halle-Wittenberg, Wolfgang-Langenbeck-Str. 406120 Halle(Saale), Germany;
3. Department of Chemistry, Faculty of Science, Chemical and Bioactivity Information Centre, University of Buea, P. O. Box 63, Buea, Cameroon;
4. Institute of Pharmaceutical Sciences, Research Group Pharmaceutical Bioinformatics, Albert-Ludwigs-Universität Freiburg, Hermann-Herder-Strasse 9, 79104 Freiburg, Germany |
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Abstract Traditional medicinal practices have a profound influence on the daily lives of people living in developing countries, particularly in Africa, since the populations cannot generally afford the cost of Western medicines. We have undertaken to investigate the correlation between the uses of plants in Traditional African medicine and the biological activities of the derived natural products, with the aim to validate the use of traditional medicine in Northern African communities. The literature is covered for the period 1959-2015 and part III of this review series focuses on plant families with names beginning with letters T to Z. The authors have focused on curating data from journals in natural products and phytomedicine. Within each journal home page, a query search based on country name was conducted. All articles ''hits'' were then verified, one at a time, that the species was harvested within the Northern African geographical regions. The current data partly constitutes the bases for the development of the Northern African natural compounds database. The review discusses 284 plant-based natural compounds from 34 species and 11 families. It was observed that the ethnobotanical uses of less than 40% of the plant species surveyed correlated with the bioactivities of compounds identified.
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| Keywords
African flora
Biological activities
Ethnobotany
Natural products
Traditional medicine
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| Fund:Financial support is acknowledged from Lhasa Ltd,Leeds,UK through the Chemical and Bioactivity Information Centre (CBIC),University of Buea,Cameroon.FNK acknowledges a Georg Forster fellowship for postdoctoral researchers from the Alexander von Humboldt Foundation,Germany |
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Issue Date: 08 February 2018
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