Further New Highly Oxidative Cembranoids from the Hainan Soft Coral <i>Sarcophyton trocheliophorum</i>

doi:10.1007/s13659-016-0088-4

Natural Products and Bioprospecting

2016, Vol. 6

Issue (2) : 97-102 DOI: 10.1007/s13659-016-0088-4

Original article

Further New Highly Oxidative Cembranoids from the Hainan Soft Coral Sarcophyton trocheliophorum

Wen-Ting Chen¹, Lin-Fu Liang², Xu-Wen Li¹, Wei Xiao³, Yue-Wei Guo¹

1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhang Jiang High-Tech Park, Shanghai 201203, People's Republic of China;
2. College of Material Science and Engineering, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha 410004, People's Republic of China;
3. Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, People's Republic of China

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Abstract Three new highly oxidative cembranoids, sarcophytrols D-F (1-3), were obtained from the South China Sea soft coral Sarcophyton trocheliophorum, along with two known related ones (4 and 5). Their structures were elucidated by extensive spectroscopic analyses and by comparison with literature data. The discovery of these new secondary metabolites enriched the family of cembranoids deduced from the title animal.

Keywords Soft coral Sarcophyton trocheliophorum Cembranoids Sarcophytrol Structure elucidation

Fund:This research work was financially supported by the National Marine "863" Projects (Nos.2013AA092902 and 2012AA092105);the Natural Science Foundation of China (Nos.81520108028,81273430,41506187,41306130,41476063),NSFC Shangdong Joint Fund for Marine Science Research Centers (Grant No.U1406402),SCTSM Project (No.14431901100 and 15431901000);the SKLDR/SIMM Projects (SIMM1203ZZ-03 and 1501ZZ-03);and was partially funded by the EU 7th Framework Programme-IRSES Project (No.246987)

Issue Date: 08 February 2018

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Wen-Ting Chen,Lin-Fu Liang,Xu-Wen Li, et al. Further New Highly Oxidative Cembranoids from the Hainan Soft Coral Sarcophyton trocheliophorum[J]. Natural Products and Bioprospecting, 2016, 6(2): 97-102.

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http://npb.kib.ac.cn/EN/10.1007/s13659-016-0088-4 OR http://npb.kib.ac.cn/EN/Y2016/V6/I2/97

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