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Chemical Constituents from the Stems of Ecdysanthera rosea |
Chang-Wei Song1,2, Paul-Keilah Lunga3, Xu-Jie Qin1,2, Gui-Guang Cheng1,2, Ya-Ping Liu1, Xiao-Dong Luo1 |
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China; 2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China; 3. Laboratory of Phytobiochemistry and Medicinal Plants Study, Department of Biochemistry, Faculty of Science, University of Yaoundé 1, P. O. Box 812, Yaoundé, Cameroon |
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Abstract One new eudesmane sesquiterpenoid(1) named ecdysantherol A and two new benzene derivatives ecdysantherols B(2) and C(3), together with five known benzene derivatives(4-8) were isolated from the stems of Ecdysanthera rosea. The structures of the new compounds were elucidated by extensive spectroscopic methods and X-ray diffraction. The known compounds were identified by the comparison of their spectroscopic data with reported literature data. Compound 1 showed moderate antibacterial activity against the Providensia smartii with MIC value of 12.5 μg/mL.
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Keywords
Ecdysanthera rosea
Sesquiterpenoid
Phenolic glycoside
Absolute configuration
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Fund:This project was supported by the National Natural Science Foundation of China(81225024), the National Science and Technology Support Program of China(2013BAI11B02). |
Issue Date: 11 February 2018
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1. |
Y. Jiang, B.T. Li, Flora of China, vol. 63 (Science Press, Beijing, 1977), p. 2342. P. Luger, M. Weber, N.X. Dung, P.T. Ky, L. Chinh, Acta. Crystallogr. 52, 1574-1576 (1996)3. D.K. Chu, T.C. Le, T.K. Pham, Tap. Chi. Duoc. Hoc. 4, 13-16 (1997)4. P. Luger, M. Weber, X.D. Nguyen, T.K. Pham, Cryst. Res. Technol. 33, 325-332 (1998)5. T.K. Pham, T.C. Le, Tap. Chi. Duoc. Hoc. 5, 14-16 (1997)6. C. Le, T. Nguyen, T.K. Pham, H. Trinh, X.D. Nguyen, P. Luger, Tap. Chi. Duoc. Hoc. 4, 16-17 (1995)7. X.D. Zhu, Q.H. Zhang, F. Wang, Y.J. Ye, Zhongcaoyao 42, 237-240 (2011)8. K.F. Huang, M.L. Sy, J.S. Lai, J. Chin. Chem. Soc. 37, 187-189 (1990)9. X.D. Zhu, Q.H. Zhang, L. Kong, F. Wang, S.D. Luo, Fitoterapia 81, 906-909 (2010)10. F.Q. Xu, H.Y. Liu, C.X. Chen, H.M. Zhong, Chem. Nat. Compd. 44, 308-316 (2008)11. F.Q. Xu, H.Y. Liu, F. Teng, C.X. Chen, H.M. Zhong, Tianran Chanwu Yanjiu Yu Kaifa 19, 365-368 (2007)12. X.D. Zhu, G.S. Wu, J.Y. Xiang, H.R. Luo, S.D. Luo, H.M. Zhu, Fitoterapia 82, 632-636 (2011)13. V.K. Phan, D.T. Mai, V.D.T. Le, H.T. Nguyen, N.H. Nguyen, Chem. Pharm. Bull. 56, 1270-1275 (2008)14. L. Lyia, P.S. Navindra, J. Agric. Food. Chem. 58, 11673-11679 (2010)15. D.G. Marina, F. Antonio, M. Pietro, P. Lucio, Synth. Commun. 28, 3693-3700 (1998)16. W.J. Liang, Q.Y. Ma, H.Z. Jiang, J. Zhou, J. Pang, Y.X. Zhao, Chin. Tradit. Herb. Drugs 42, 1271-1275 (2011)17. T.S. Wu, J.H. Yeh, P.L. Wu, Phytochemistry 40, 121-124 (2011)18. G. Fang, C.P. Tang, Y. Yang, Helv. Chim. Acta 91, 1023-1030 (2008)19. Q.A. Zheng, M. Xu, C.R. Yang, D. Wang, H.Z. Li, H.T. Zhu, Y.J. Zhang, Nat. Prod. Bioprospect. 2, 111-116 (2012)20. S. Britta, S. Silke, H. Josef, K. Nasser, H. Sonja, M. Christa, J. Nat. Prod. 65, 1479-1485 (2002)21. W. Tsutomu, N. Yoshimi, N. Tadataka, Chem. Pharm. Bull. 54, 14-20 (2006)
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