New benzene derivatives from cultures of ascomycete <i>Daldinia concentrica</i>

doi:10.1007/s13659-013-0048-1

Natural Products and Bioprospecting

2013, Vol. 3

Issue (4) : 150-153 DOI: 10.1007/s13659-013-0048-1

Regular Article

New benzene derivatives from cultures of ascomycete Daldinia concentrica

Tao FENG^a, Zheng-Hui LI^a, Xia YIN^a,b, Ze-Jun DONG^a, Gang-Qiang WANG^c, Xing-Yao LI^a, Yan LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b University of Chinese Academy of Sciences, Beijing 100049, China;
c School of Chemistry and Chemical Engineering of Hunan University, Changsha 410082, China

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Abstract Three new benzene derivatives, named daldins A-C (1-3), together with a known analogue, 2-hydroxymethyl-3-(1-hydroxypropyl) phenol (4) have been isolated from cultures of ascomycete Daldinia concentrica. The structures of 1-4 with absolute configuration were established by means of spectroscopic methods and X-ray diffraction. All compounds showed no significant inhibition on five human cancer cell lines with IC₅₀ values > 40 μmol.

Keywords Daldinia concentrica benzene derivatives absolute configuration

Fund:This project was supported by the National Basic Research Program of China (973 Program, 2009CB522300), the National Natural Sciences Foundation of China (30830113, 81102346), and Youth Innovation Promotion Association CAS.

Issue Date: 11 February 2018

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	Tao FENG
	Zheng-Hui LI
	Xia YIN
	Ze-Jun DONG
	Gang-Qiang WANG
	Xing-Yao LI
	Yan LI
	Ji-Kai LIU

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Tao FENG,Zheng-Hui LI,Xia YIN, et al. New benzene derivatives from cultures of ascomycete Daldinia concentrica[J]. Natural Products and Bioprospecting, 2013, 3(4): 150-153.

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http://npb.kib.ac.cn/EN/10.1007/s13659-013-0048-1 OR http://npb.kib.ac.cn/EN/Y2013/V3/I4/150

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