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Two New Steroidal Saponins from Ypsilandra thibetica |
| Yong-Ai Si1,2, Huan Yan1, Wei Ni1, Zhen-Hua Liu1,2, Ting-Xiang Lu1, Chang-Xiang Cheng1, Hai-Yang Liu1 |
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China |
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Abstract Two new monosaccharide steroidal saponins, named ypsilandroside S(1) and ypsilandroside T(2), have been isolated from the whole plants of Ypsilandra thibetica. Their structures were elucidated as heloniogenin 3-O-β-D-apiofuranoside(1) and pregna 5, 16-dien-3β, 12α-diol-20-one-3-O-β-D-apiofuranoside(2) by spectroscopic techniques(1D and 2D NMR, MS). Compounds 1 and 2 were tested for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells.
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| Keywords
Ypsilandra thibetica
Liliaceae
Ypsilandroside S
Ypsilandroside T
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| Fund:This work was financially supported by the National Natural Science Funding of China(No. 31170333) and the Natural Science Foundation of Yunnan Province(No. 2009CC019). |
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Issue Date: 11 February 2018
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