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Twelve new compounds from the basidiomycete Boreostereum vibrans |
| Jian-Hai DINGa,b,c, Tao FENGa, Zheng-Hui LIa, Liang LIb, Ji-Kai LIUa |
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;
c Graduate University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Seven cadinane sesquiterpenoids, named boreovibrins A-G(1-7), three dihydrobenzofurans(8-10), and two lactones(11 and 12), together with one known compound(13), were isolated from cultures of the basidiomycete Boreostereum vibrans. The new structures were elucidated by means of spectroscopic methods. Compounds 5, 6, and 11 showed weak inhibitory activities against isozymes of 11β-hydroxysteroid dehydrogenases(11β-HSD).
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| Keywords
cadinane
sesquiterpenoid
boreovibrin
dihydrobenzofuran
lactone
Boreostereum vibrans
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| Fund:This work was financially supported by National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Science Foundation of China(30830113, U1132607). |
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Issue Date: 11 February 2018
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