| Regular Article |
|
|
|
|
|
Non-isoprenoid botryane sesquiterpenoids from basidiomycete Boletus edulis and their cytotoxic activity |
| Tao FENGa, Zheng-Hui LIa, Ze-Jun DONGa, Jia SUa,b, Yan LIa, Ji-Kai LIUa |
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate School of Chinese Academy of Sciences, Beijing 100039, China |
|
|
|
|
Abstract Three non-isoprenoid botryane sesquiterpenoids, named boledulins A-C(1-3), have been isolated from the cultures of basidiomycete Boletus edulis Bull. The structures were established by means of spectroscopic methods. Boledulin A(1) exhibited moderate inhibitory activity against five human cancer cell lines.
|
| Keywords
botryane
sesquiterpenoid
boledulin
Boletus edulis
|
| Fund:This work was supported in part by the National Natural Sci This project was supported by the National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Sciences Foundation of China(30830113), and MOST(2009ZX09501-029). |
|
Issue Date: 10 November 2017
|
|
|
| [1] |
(a) Fehlhaber, H. W.; Geipel, R.; Mercker, H. J.; Tschesche, R.; Welmar, K.; Schoenbeck, F. Chem. Ber. 1974, 107, 1720-1730; (b) Collado, I. G.; Hernandez-Galan, R.; Prieto, V.; Hanson, J. R.; Rebordinos, L. G. Phytochemistry 1996, 41, 513-517; (c) DuranPatron, R.; Hernandez-Galin, R.; Rebordinos, L. G.; Cantoral, J. M.; Collado, I. G. Tetrahedron 1999, 55, 2389-2400.
|
| [2] |
Qin, X. D.; Shao, H. J.; Dong, Z. J.; Liu, J. K. J. Antibiot. 2008, 61, 556-562.
|
| [3] |
(a) Duran-Patrón, R.; Hernandez-Galan, R.; Collado, I. G. J. Nat. Prod. 1999, 63, 182-184; (b) Reino, J. L.; Duran-Patron, R.; Segura, I.; Hernandez-Galan, R.; Riese, H. H.; Collado, I. G. J. Nat. Prod. 2003, 66, 344-349; (c) Collado, I. G.; HernandezGalan, R.; Prieto, V.; Hanson, J. R.; Rebordinos, L. G. Phytochemistry 1996, 41, 513-517; (d) Rebordinos, L.; Cantoral, J. M.; Prieto, V.; Hanson, J. R.; Collado, I. G. Phytochemistry 1996, 42, 383-387.
|
| [4] |
Kunisch, F.; Hobert, K.; Welzel, P. Tetrahedron Lett. 1985, 26, 5433-5436.
|
| [5] |
Hanson, J. R.; Nyfeler, R. J. Chem. Soc., Chem. Comm. 1976, 72-73.
|
| [6] |
(a) Collado, I. G.; Aleu, J.; Macias-Sanchez, A. J.; HernandezGalan, R. J. Chem. Ecol. 1994, 20, 2631-2644; (b) Wang, C. M.; Hopson, R.; Lin, X.; Cane, D. E. J. Am. Chem. Soc. 2009, 131, 8360-8361.
|
| [7] |
Mosmann, T. J. Immunol. Methods 1983, 65, 55-63.
|
| [8] |
Reed, L. J.; Muench, H. Am. J. Hyg. 1938, 27, 493-497.
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
