Xylanilyticolides A-C, Three New Compounds from Cultures of the Actinomycete <i>Promicromonospora xylanilytica</i> YIM 61515

doi:10.1007/s13659-018-0154-1

Natural Products and Bioprospecting

2018, Vol. 8

Issue (2) : 91-95 DOI: 10.1007/s13659-018-0154-1

ORIGINAL ARTICLES

Xylanilyticolides A-C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515

Zhen-Xiong Wang¹, Shen Qin², Li-Hua Xu², He-Ping Chen¹, Huan Sun¹, Rong Huang¹, Zheng-Hui Li¹, Tao Feng¹, Ji-Kai Liu¹

1 School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China;
2 Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, China

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Abstract Three new lactones, xylanilyticolides A-C (1-3), were isolated from cultures of the actinomycete Promicromonospora xylanilytica YIM 61515. Their structures were elucidated by 1D and 2D NMR spectroscopic data in conjunction with HRESIMS analysis. Compound 1 exhibited potent cytotoxicities against five human cancer cell lines HL-60, A-549, SMMC-7721, MCF-7 and SW480 with the IC₅₀ values of 3.9, 15.2, 11.2, 5.9, and 4.7 μM, respectively.

Keywords Actinomycete Promicromonospora xylanilytica Xylanilyticolides Cytotoxicity

Fund:This work was financially supported by National Natural Science Foundation of China (81561148013, 21502239), the Key Projects of Technological Innovation of Hubei Province (No. 2016ACA138), and the Fundamental Research Funds for the Central University, South-Central University for Nationalities (CZZ17006, CZQ17008). The authors thank Analytical & Measuring Centre, South-Central University for Nationalities, for the NMR measurements.

Corresponding Authors: Tao Feng, Ji-Kai Liu E-mail: tfeng@mail.scuec.edu.cn;jkliu@mail.kib.ac.cn

Issue Date: 26 April 2018

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	Zhen-Xiong Wang
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	Li-Hua Xu
	He-Ping Chen
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	Rong Huang
	Zheng-Hui Li
	Tao Feng
	Ji-Kai Liu

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Zhen-Xiong Wang,Shen Qin,Li-Hua Xu, et al. Xylanilyticolides A-C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515[J]. Natural Products and Bioprospecting, 2018, 8(2): 91-95.

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http://npb.kib.ac.cn/EN/10.1007/s13659-018-0154-1 OR http://npb.kib.ac.cn/EN/Y2018/V8/I2/91

1. U.R. Abdelmohsen, K. Bayer, U. Hentschel, Nat. Prod. Rep. 31, 381-399 (2014)
2. O. Genilloud, Nat. Prod. Rep. 34, 1203-1232 (2017)
3. P.B. Gupta, T.T. Onder, G. Jiang, K. Tao, C. Kuperwasser, R.A. Weinberg, E.S. Lander, Cell 138, 645-659 (2009)
4. Y. Miyazaki, M. Shibuya, H. Sugawara, O. Kawaguchi, C. Hirose, J. Nagatsu, S. Esumi, J. Antibiot. 27, 814-821 (1974)
5. L. Lazzarini, G. Cavaletti, F. Toppo, Marinelli. Antonie Van Leeuwenhoek 78, 399-405 (2000)
6. J. Clardy, M.A. Fischbach, C.T. Walsh, Nat. Biotechnol. 24, 1541-1550 (2006)
7. N.A. Krasil'nikov, L.V. Kalakutskii, N.F. Kirillova, Bull. Acad. Sci. USSR Ser. Biol. 1, 107-112 (1961)
8. M. Izumikawa, M. Takagi, K. Shin-Ya, J. Antibiot. 64, 689-691 (2011)
9. S. Qin, J.H. Jiang, H.P. Klenk, W.Y. Zhu, G.Z. Zhao, L.X. Zhao, S.K. Tang, L.H. Xu, W.J. Li, Int. J. Syst. Evol. Micr. 62, 84-89 (2012)
10. H. Fujimoto, Y. Okamoto, E. Sone, S. Maeda, K. Akiyama, M. Ishibashi, Chem. Pharm. Bull. 53, 923-929 (2005)
11. T. Mosmann, J. Immunol. Methods 65, 55-63 (1983)
12. L.J. Reed, H. Muench, Am. J. Hyg. 27, 493-497 (1938)

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