Natural Products and Bioprospecting    2019, Vol. 9 Issue (2) : 77-137     DOI: 10.1007/s13659-019-0201-6
REVIEW |
The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review
Joseph Sakah Kaunda1,2, Ying-Jun Zhang1,3
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
2 Graduate School of the Chinese Academy of Sciences, Beijing 100039, People's Republic of China;
3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
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Abstract  Over the past 30 years,the genus Solanum has received considerable attention in chemical and biological studies.Solanum is the largest genus in the family Solanaceae,comprising of about 2000 species distributed in the subtropical and tropical regions of Africa,Australia,and parts of Asia,e.g.,China,India and Japan.Many of them are economically significant species.Previous phytochemical investigations on Solanum species led to the identification of steroidal saponins,steroidal alkaloids,terpenes,flavonoids,lignans,sterols,phenolic comopunds,coumarins,amongst other compounds.Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to different tumors as breast cancer (4T1 and EMT),colorectal cancer (HCT116,HT29,and SW480),and prostate cancer (DU145) cell lines.The biological activities have been attributed to a number of steroidal saponins,steroidal alkaloids and phenols.This review features 65 phytochemically studied species of Solanum between 1990 and 2018,fetched from SciFinder,Pubmed,ScienceDirect,Wikipedia and Baidu,using "Solanum" and the species'names as search terms ("all fields").
Keywords Solanum      Solanaceae      Phytochemistry      Steroidal saponins and alkaloids      Ethnopharmacology     
Corresponding Authors: Ying-Jun Zhang     E-mail: zhangyj@mail.kib.ac.cn
Issue Date: 04 April 2019
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Joseph Sakah Kaunda,Ying-Jun Zhang. The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review[J]. Natural Products and Bioprospecting, 2019, 9(2): 77-137.
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http://npb.kib.ac.cn/EN/10.1007/s13659-019-0201-6     OR     http://npb.kib.ac.cn/EN/Y2019/V9/I2/77
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