Natural Products and Bioprospecting    2019, Vol. 9 Issue (6) : 357-392     DOI: 10.1007/s13659-019-00222-3
REVIEW |
The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review
Xiao-Rui Zhang1,2, Joseph Sakah Kaunda1,2, Hong-Tao Zhu1, Dong Wang1, Chong-Ren Yang1, Ying-Jun Zhang1,3
1 State Key Laboratory of Phytochemistry and Plant Resources in West China. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
2 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China;
3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
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Abstract  Terminalia Linn, a genus of mostly medium or large trees in the family Combretaceae with about 250 species in the world, is distributed mainly in southern Asia, Himalayas, Madagascar, Australia, and the tropical and subtropical regions of Africa. Many species are used widely in many traditional medicinal systems, e.g., traditional Chinese medicine, Tibetan medicine, and Indian Ayurvedic medicine practices. So far, about 39 species have been phytochemically studied, which led to the identification of 368 compounds, including terpenoids, tannins, flavonoids, phenylpropanoids, simple phenolics and so on. Some of the isolates showed various bioactivities, in vitro or in vivo, such as antitumor, anti HIV-1, antifungal, antimicrobial, antimalarial, antioxidant, diarrhea and analgesic. This review covers research articles from 1934 to 2018, retrieved from SciFinder, Wikipedia, Google Scholar, Chinese Knowledge Network and Baidu Scholar by using "Terminalia" as the search term ("all fields") with no specific time frame setting for the search. Thirty-nine important medicinal and edible Terminalia species were selected and summarized on their geographical distribution, traditional uses, phytochemistry and related pharmacological activities.
Keywords Terminalia      Combretaceae      Ethnomedicine      Traditional uses      Phytochemistry      Hydrolyzable tannins      Pharmacology     
Fund:This work was supported by the Key Projects of Yunnan Science and Technology, and Yunnan Key Laboratory of Natural Medicinal Chemistry (S2017-ZZ14).
Corresponding Authors: Ying-Jun Zhang     E-mail: zhangyj@mail.kib.ac.cn
Issue Date: 11 December 2019
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Xiao-Rui Zhang,Joseph Sakah Kaunda,Hong-Tao Zhu, et al. The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review[J]. Natural Products and Bioprospecting, 2019, 9(6): 357-392.
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http://npb.kib.ac.cn/EN/10.1007/s13659-019-00222-3     OR     http://npb.kib.ac.cn/EN/Y2019/V9/I6/357
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