Three new indole alkaloids from <i>Rauvolfia yunnanensis</i>

doi:10.1007/s13659-011-0023-7

Natural Products and Bioprospecting

2011, Vol. 1

Issue (3) : 104-107 DOI: 10.1007/s13659-011-0023-7

Regular Article

Three new indole alkaloids from Rauvolfia yunnanensis

Yuan GAO^a,b,c, Fei WANG^a,b, Dong-Sheng ZHOU^b, Yan LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b BioBioPha Co., Ltd., Kunming 650201, China;
c Graduate University of Chinese Academy of Sciences, Beijing 100049, China

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Abstract One rare tetracyclic macroline-type indole alkaloid, named rauvoyunine A(1), and two new picraline-type alkaloids rauvoyunines B and C(2 and 3) were isolated from the aerial parts of Rauvolfia yunnanensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines.

Keywords Rauvolfia yunnanensis indole alkaloid rauvoyunine

Fund:This work was financially supported by National Basic Research Program of China(973 Program)2009CB522300, the "West Light" program of Chinese Academy of Sciences, and Natural Product Library Program of BioBioPha.

Issue Date: 11 February 2018

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Yuan GAO,Fei WANG,Dong-Sheng ZHOU, et al. Three new indole alkaloids from Rauvolfia yunnanensis[J]. Natural Products and Bioprospecting, 2011, 1(3): 104-107.

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http://npb.kib.ac.cn/EN/10.1007/s13659-011-0023-7 OR http://npb.kib.ac.cn/EN/Y2011/V1/I3/104

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