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Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens |
| Zhen-Zhu Zhao1,2, He-Ping Chen1,2, Tao Feng1, Zheng-Hui Li1, Ze-Jun Dong1, Ji-Kai Liu1 |
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China |
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Abstract Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol(1), 11-hydroxyacetoxydrim-7-en-3β-ol(2), 2, 6-dimethyl-7, 10-epoxy-10-hydroxymethyldodeca-2, 11-dien-6-ol(3), and 7, 10-epoxy-2, 6, 10-trimethyldodeca-2, 11-diene-4, 6-diol(4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.
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| Keywords
Phellinidium sulphurascens
Drimane
7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene
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| Fund:This work was financially supported by National Natural Science Foundation of China(U1132607, 81102346), and Natural Science Fund of Yunnan province(2011FB099). |
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Issue Date: 11 February 2018
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