Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus <i>Arthrinium</i> sp. HS66

doi:10.1007/s13659-020-00248-y

Natural Products and Bioprospecting

2020, Vol. 10

Issue (4) : 201-207 DOI: 10.1007/s13659-020-00248-y

ORIGINAL ARTICLES

Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

Xiao-Zheng Su^1,2,3, Jian-Wei Tang^1,2, Kun Hu^1,2, Xiao-Nian Li^1,2, Han-Dong Sun^1,2, Pema-Tenzin Puno^1,2

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

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Abstract Arthrinins E-G (1-3), three new sesquiterpenoids possessing non-isoprenoid botryane skeleton, were isolated from the fermentation of an endophytic fungus named Arthrinium sp. HS66 which colonized in the stems of Isodon xerophilus. Their structures were determined by extensive spectroscopic methods. Furthermore, the structure of 1 was unambiguously confirmed by X-ray diffraction, while those of 2 and 3 were verified through quantum chemical calculation of NMR data and ECD spectra.

Keywords Isodon xerophilus Endophytic fungus Arthrinium Botryane sesquiterpenoid Quantum chemical calculation

Fund:This project was supported financially by the National Natural Science Foundation of China (No. 81874298), the CAS "Light of West China" program (Pema-Tenzin Puno), and the Yunnan Science Fund for Distinguished Young Scholars (2019FJ002).

Corresponding Authors: Pema-Tenzin Puno E-mail: punopematenzin@mail.kib.ac.cn

Issue Date: 19 August 2020

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Xiao-Zheng Su,Jian-Wei Tang,Kun Hu, et al. Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66[J]. Natural Products and Bioprospecting, 2020, 10(4): 201-207.

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http://npb.kib.ac.cn/EN/10.1007/s13659-020-00248-y OR http://npb.kib.ac.cn/EN/Y2020/V10/I4/201

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