Regular Article |
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Flavonoid oligomers from Chinese dragon's blood, the red resins of Dracaena cochinchinensis |
Qing-An ZHENGa, Min XUa, Chong-Ren YANGa,b, Dong WANGa, Hai-Zhou LIa, Hong-Tao ZHUa, Ying-Jun ZHANGa |
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; b Weihe Biotech Laboratory, Yuxi 653100, China |
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Abstract A detailed chemical investigation of the red resins from Dracaena cochinchinensis(Chinese dragon's blood) yielded five new flavonoid oligomers, named cochinchinenins D-H(1-5), together with a known biflavonoid, cinnabarone(6), and a mixture of two known biflavonoids, socotrin-4'-ol(7) and homoisosocotrin-4'-ol(8). Of these new compounds, 1-3 were biflavonoids and 4 and 5 were triflavonoids. Their structures were determined on the basis of spectroscopic analysis. The isolated compounds were tested for cytotoxicity(Cdc25), antibacterial(PEPT) and antifungal(YNG) activities.
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Keywords
Dracaena cochinchinensis
flavonoid oligomers
cochinchinenins D-H
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Fund:This work was supported by the 973 Program of Ministry of Science and Technology of China(2011CB915503), the Fourteenth Candidates of the Young Academic Leaders of Yunnan Province(Min XU, 2011CI044), and NSFC 31060054. |
Issue Date: 11 February 2018
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