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Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla |
Ling-Yu Jin1,2, Ting-Xiang Lu22, . Xu-Jie Qin2, Wei Ni2, Huan Yan3, Yu Chen3, Hui Liu1, Hong-Ping He2 |
1. College of Pharmacy and Chemistry, Dali University, Dali 671000, China; 2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; 3. University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested.
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Keywords
Paris polyphylla var. stenophylla
Liliaceae
Spirostanol saponins
Paristenoside A
Paristenoside B
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Fund:This work is funded by the National Natural Science Funding of China (Grand No.31570363);the Key Research Program of the Chinese Academy of Sciences (Grand No.KSZDEW-Z-004-03-4),and the Natural Science Foundation of Yunnan Province (Grand No.2015FA031) |
Issue Date: 08 February 2018
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