| Regular Article |
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Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum |
| Ming-Ming LI, Kou WANG, Juan HE, Li-Yan PENG, Xuan-Qin CHEN, Xiao CHENG, Qin-Shi ZHAO |
| State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China |
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Abstract Four new labdane-type diterpenoid glycosides, laevissiosides A-D (1-4) were isolated from the 95% ethanol extract of Diplopterygium laevissimum (Christ) Nakai, along with two known analogues, 18-β-D-glucopyranosyl ester-sclareol (5) and 18-hydroxy-sclareol (6). The structures of compounds 1-4 were elucidated by extensive 1D and 2D NMR spectroscopy as well as high-resolution MS analyses. All isolated compounds were evaluated for their cytotoxic effects.
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| Keywords
Diplopterygium laevissimum
labdane-type diterpenoid glycosides
laevissiosides
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| Fund:This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2009CB522303 and 2011CB915503), the National Natural Science Foundation of China (Nos. 90813004 and U0932602), the projects from Chinese Academy of sciences (Nos. 2009311211011 and 2009312311024), and the State Key Laboratory of Phytochemistry and Plant Resources in West China (No. P2010-ZZ05). |
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Issue Date: 11 February 2018
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