| Regular Article |
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Steroidal and pregnane glycosides from Ypsilandra thibetica |
| Hai-Yang LIU, Chang-Xiang CHEN, Yi LU, Jun-Yun YANG, Wei NI |
| State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China |
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Abstract The whole plants of Ypsilandra thibetica have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of two new bisdesmosidic furostanol saponins, named ypsilandroside P(1) and ypsilandroside Q(2), and one new pregnane glycoside, named ypsilandroside R(3), together with nine known steroidal glycosides. Their structures were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic hydrolysis. Ypsilandroside P(1) was cytotoxicity against two human tumor cell lines.
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| Keywords
Ypsilandra thibetica
Liliaceae
furostanol glycoside
pregnane glycoside
ypsilandroside
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| Fund:This work was financially supported by National Natural Science Funding of China(No. 31170333), the Natural Science Foundation of Yunnan Province(No. 2009CC019), the West Light Foundation of the Chinese Academy of Sciences(No. 2908025712W1), and a fund(No. 540806321211) of State Key Laboratory of Phytochemistry and Plant Resources in West China, Germplasm Bank of Wild Species and CAS Innovation Program of Kunming Institute of Botany. |
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Issue Date: 11 February 2018
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