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A Fragmentation Study on Four Oligostilbenes by Electrospray Tandem Mass Spectrometry |
| Chen-Chen Zhang1,2,3, Chang-An Geng1,2, Ji-Jun Chen1,2,3 |
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Kunming 650201, Yunnan, People's Republic of China;
2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People's Republic of China;
3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China |
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Abstract Oligostilbenes have attracted much interest due to their intricate structures and diverse bioactivities. In this study, two stilbene dimers, (-)-7,8-cis-ε-viniferin (1) and carasiphenol A (2), and two trimers, suffruticosol A (3) and suffruticosol C (4), were investigated by electrospray ionization ion-trap time-of-flight multistage mass spectrometry (ESI-IT-TOF-MSn). Based on the MSn study, the fragmentation pathways and diagnostic ions of four oligostilbenes in both positive and negative modes were proposed. The consecutive elimination of phenol (C6H6O) and resorcinol (C6H6O2) moieties were the particular dissociation for oligostilbenes due to the presence of 1,2-diphenylethylene nucleus. The present MSn fragmentation study will provide valuable information for the fast characterization of oligostilbenes from complicated natural mixtures.
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| Keywords
ESI-IT-TOF-MSn
Fragmentation rules
Oligostilbenes
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| Fund:This work was financially supported by the National Natural Science Foundation of China (81773609), the Program of Yunling Scholarship, and the Applied Basic Research Programs of Yunnan Province (2017FB137). |
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Corresponding Authors:
Chang-An Geng, Ji-Jun Chen
E-mail: gengchangan@mail.kib.ac.cn;chenjj@mail.kib.ac.cn
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Issue Date: 09 August 2019
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