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Five new sucrose esters from the whole plants of Phyllanthus cochinchinensis |
Jian-Qiang ZHAOa,b, Yan-Ming WANGa,b, Dong WANGa, Chong-Ren YANGa, Min XUa, Ying-Jun ZHANGa |
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; b University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of five new sucrose benzoyl esters, 3,6'-di-O-benzoylsucrose (1), 3,6'-di-O-benzoyl-2'-O-acetylsucrose (2), 3,6'-di-O-benzoyl-4'-Oacetylsucrose (3), 3,6'-di-O-benzoyl-3'-O-acetylsucrose (4) and 3-O-benzoyl-6'-O-(E)-cinnamoylsucrose (5), together with two known secoiridoid glycosides, jasminoside (6) and jaslanceoside B (7). Their structures were established on the basis of detailed spectroscopic analysis and chemical method.
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Keywords
Phyllanthus cochinchinensis
sucrose esters
secoiridoid glycosides
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Fund:The authors are grateful to the members of the Analytical Group in State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, for measurements of all spectra. We would like to acknowledge Prof. Yan Li for cytotoxicity assay. This work was supported by the NSFC 21002105, the 973 Program of Ministry of Science and Technology of China (2011CB915503), the Fourteenth Batch Candidates of the Young Academic Leaders of Yunnan Province (Min XU, 2011CI044) and by West Light Foundation of the Chinese Academy of Sciences. |
Issue Date: 11 February 2018
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[1] |
Zhang, Y. J.; Tanaka, T.; Iwamoto, Y.; Yang, C. R.; Kouno, I. J. Nat. Prod. 2000, 63, 1507-1510.
|
[2] |
Zhang, Y. J.; Abe, T.; Tanaka, T.; Yang, C. R.; Kouno, I. J. Nat. Prod. 2001, 64, 1527-1532.
|
[3] |
Ratnayake, R.; Covell, D.; Ransom, T. T.; Gustafson, K. R.; Beutler, J. A. Org. Lett. 2009, 11, 57-60.
|
[4] |
Liu, Q.; Wang, Y. F.; Chen, R. J.; Zhang, M. Y.; Wang, Y. F.; Yang, C. R.; Zhang, Y. J. J. Nat. Prod. 2009, 72, 969-972.
|
[5] |
Pettit, G. R.; Schaufelberger, D. E.; Nieman, R. A.; Dufresne, C.; Saenz-Renauld, J. A. J. Nat. Prod. 1990, 53, 1406-1413.
|
[6] |
Shen, Y. C.; Lin, S. L. Planta Med. 1996, 62, 515-518.
|
[7] |
Shen, Y. C.; Lin, S. L.; Chen, C. C. Phytochemistry 1997, 44, 891-895.
|
[8] |
Dong, L. B.; He, J.; Li, X. Y.; Wu, X. D.; Deng, X.; Xu, G.; Peng, L. Y.; Zhao, Y.; Li, Y.; Gong, X.; Zhao, Q. S. Nat. Prod. Bioprospect. 2011, 1, 41-47.
|
[9] |
Chang, S. L.; Chang, C. L.; Chiang, Y. M.; Hsieh, R. H.; Tzeng, C. R.; Wu, T. K.; Sytwu, H. K.; Shyur, L. F.; Yang, W. C. Planta Med. 2004, 70, 1045-1051.
|
[10] |
Reed, L. J.; Muench, H. Am. J. Hyg. 1938, 27, 493-497.
|
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