New <i>Lycopodium</i> alkaloids from <i>Lycopodium obscurum</i>

doi:10.1007/s13659-013-0015-x

Natural Products and Bioprospecting

2013, Vol. 3

Issue (2) : 52-55 DOI: 10.1007/s13659-013-0015-x

Regular Article

New Lycopodium alkaloids from Lycopodium obscurum

Xue-Yuan ZHANG^a,b, Liao-Bin DONG^a,b, Fei LIU^a,b, Xing-De WU^a, Juan HE^a, Li-Yan PENG^a, Huai-Rong LUO^a, Qin-Shi ZHAO^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b University of Chinese Academy of Sciences, Beijing 100049, China

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Abstract Three new Lycopodium alkaloids, obscurumines C-E (1-3), along with nine known compounds, were isolated from the club moss Lycopodium obscurum L. Structures of the new compounds were determined on the basis of their spectroscopic analysis and the relative configurations of 1 were established by X-ray crystallographic analysis. All the new isolates were tested for the acetylcholinesterase (AChE) inhibitory activity.

Keywords obscurumines Lydopodium alkaloids Lycopodium obscurum acetylcholinesterase (AChE) inhibitory activity

Fund:This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2011CB915503 and 2009CB522303) and the National Natural Science Foundation of China (Nos. U0932602 and 90813004).

Issue Date: 11 February 2018

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	Xue-Yuan ZHANG
	Liao-Bin DONG
	Fei LIU
	Xing-De WU
	Juan HE
	Li-Yan PENG
	Huai-Rong LUO
	Qin-Shi ZHAO

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Xue-Yuan ZHANG,Liao-Bin DONG,Fei LIU, et al. New Lycopodium alkaloids from Lycopodium obscurum[J]. Natural Products and Bioprospecting, 2013, 3(2): 52-55.

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http://npb.kib.ac.cn/EN/10.1007/s13659-013-0015-x OR http://npb.kib.ac.cn/EN/Y2013/V3/I2/52

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