Dammarane-type saponins from steamed leaves of <i>Panax notoginseng</i>

doi:10.1007/s13659-011-0036-2

Natural Products and Bioprospecting

2011, Vol. 1

Issue (3) : 124-128 DOI: 10.1007/s13659-011-0036-2

Regular Article

Dammarane-type saponins from steamed leaves of Panax notoginseng

Qing LIU^a, Jun-Jiang LV^a,b, Min XU^a, Dong WANG^a, Hong-Tao ZHU^a, Chong-Ren YANG^a,c, Ying-Jun ZHANG^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100049, China;
c Weihe Biotech Research and Development Center, Yuxi 653101, China

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Abstract Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt₁-SFt₄(1-4) were isolated from the steamed leaves of Panax notoginseng(Burk.) F. H. Chen(Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses and acidic hydrolysis. The known ginsenosides Rk₂ and Rh3 were obtained from P. notoginseng for the first time. All of these new saponins showed no in vitro cytotoxicity against five human cancer cell lines(HL-60, SMMC-7712, A-549, MCF-7, and SW480).

Keywords Panax notoginseng steamed leave dammarane-type saponin notoginsenoside

Fund:The authors are grateful to the members of the analytical group at State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring all the spectroscopic data. This work was supported by the 973 Program of Ministry of Science and Technology of China(2011CB915503).

Issue Date: 11 February 2018

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Qing LIU,Jun-Jiang LV,Min XU, et al. Dammarane-type saponins from steamed leaves of Panax notoginseng[J]. Natural Products and Bioprospecting, 2011, 1(3): 124-128.

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http://npb.kib.ac.cn/EN/10.1007/s13659-011-0036-2 OR http://npb.kib.ac.cn/EN/Y2011/V1/I3/124

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