Norsesquiterpenoids from the leaves of <i>Croton tiglium</i>

doi:10.1007/s13659-011-0035-3

Natural Products and Bioprospecting

2011, Vol. 1

Issue (3) : 134-137 DOI: 10.1007/s13659-011-0035-3

Short Communication

Norsesquiterpenoids from the leaves of Croton tiglium

Wei BU^a,c, Yan-Ni SHI^a,b, Yong-Ming YAN^a, Qing LU^a, Guang-Ming LIU^c, Yan LI^a, Yong-Xian CHENG^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100049, China;
c Faculty of Pharmacy, Dali University, Dali 671000, China

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Abstract Two new compounds, badounoids A(1) and B(2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active.

Keywords Croton tiglium badounoid norsesquiterpenoid cytostatic activity

Fund:This work was supported by grants(20925205, 21062026, 2010GA014 and 2009CB522300) from National Natural Science Foundation of China, Yunnan Province and National Basic Research Program of China(973 Program).

Issue Date: 11 February 2018

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	Yong-Xian CHENG

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Wei BU,Yan-Ni SHI,Yong-Ming YAN, et al. Norsesquiterpenoids from the leaves of Croton tiglium[J]. Natural Products and Bioprospecting, 2011, 1(3): 134-137.

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http://npb.kib.ac.cn/EN/10.1007/s13659-011-0035-3 OR http://npb.kib.ac.cn/EN/Y2011/V1/I3/134

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