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3,4-Secocycloartane Triterpenoids from the Cones of Pseudolarix amabilis |
| Si-Jia Xiao1, Bo Li1,2, Zheng-Rui Huang3, Wen-Lin Yuan1, Ji Ye1, Hui-Liang Li1, Xi-Ke Xu1, Yun-Heng Shen1, Wei-Dong Zhang1,2 |
1 Department of Phytochemistry, School of Pharmacy, Naval Medical University(Second Military Medical University), Shanghai 200433, China;
2 State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai 201203, China;
3 Department of Applied Chemistry, Xi'an University of Technology, Xi'an 710048, China |
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Abstract Four new 3,4-secocycloartane triterpenoids, pseudolactones A-D (1-4), were isolated from the ethanol extract of the cones of Pseudol arixamabilis. Their structures were established by extensive 1D- and 2D-NMR experiments. The cones of P. arixamabilis are enriched in the ring-expanded or cleaved cycloartane triterpenoids. This work provides new insight into cycloartane triterpenoids from the cones of P. arixamabilis.
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| Keywords
Pseudol arixamabilis
Triterpenoids
3,4-Secocycloartane
Pseudolactones A-D
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| Fund:The work was supported by NSFC (31870327, 81230090, 81520108030, 1302658), National Major Project of China (2018ZX09731016-005), The Key Research and Development Program of China (2017YFC1702002, 2017YFC1700200), Professor of Chang Jiang Scholars Program, Scientific Foundation of Shanghai China (17431902800, 16401901300), Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300). |
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Corresponding Authors:
Yun-Heng Shen, Wei-Dong Zhang
E-mail: shenyunheng@hotmail.com;wdzhangy@hotmail.com
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Issue Date: 11 March 2021
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1. Editor committee, Flora of China, vol. 7 (Science Press, Beijing, 1978), pp. 196-200
2. G.P. Ni, Zhongguo Zhongyao Zazhi 3, 156-158 (1957)
3. P. Chiu, L.T. Leung, B.C.B. Ko, Nat. Prod. Rep. 27, 1066-1083 (2010)
4. Z.L. Li, K. Chen, D.J. Pan, G.G. Xu, Acta. Chim. Sin. 47, 258-261 (1989)
5. S.P. Yang, Y. Wu, J.M. Yue, J. Nat. Prod. 65, 1041-1044 (2002)
6. Z.L. Li, D.J. Pan, C.Q. Hu, Q.L. Wu, S.S. Yang, G.Q. Xu, Acta. Chim. Sin. 40, 447-457 (1982)
7. Z.L. Li, K. Chen, D.J. Pan, G.Q. Xu, Acta. Chim. Sin. 43, 786-788 (1985)
8. G.F. Chen, Z.L. Li, D.J. Pan, J. Nat. Prod. 56, 1114-1122 (1993)
9. G.F. Chen, Z.L. Li, C.M. Tang, X. He, K. Chen, D.J. Pan, C.Q. Hu, D.R. McPhail, A.T. McPhail, K.H. Lee, Heterocycles 31, 1903-1906 (1990)
10. E. Li, A.M. Clark, C.D. Hufford, J. Nat. Prod. 58, 57-67 (1995)
11. B. Li, D.Y. Kong, Y.H. Shen, K.L. Fu, R.C. Yue, Z.Z. Han, H. Yuan, Q.X. Liu, L. Shan, H.L. Li, X.W. Yang, W.D. Zhang, Chem. Commun. 49, 1187-1189 (2013)
12. B. Li, D.Y. Kong, Y.H. Shen, H. Yuan, R.C. Yue, Y.R. He, L. Lu, L. Shan, H.L. Li, J. Ye, X.W. Yang, J. Su, R.H. Liu, W.D. Zhang, Org. Lett. 14, 5432-5435 (2012)
13. X.T. Zhao, M.H. Yu, S.Y. Shi, C. Lei, A.J. Hou, Phytochemistry 171, 112229 (2020) |
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