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Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi |
Timo H. J. NIEDERMEYER, Thomas JIRA, Michael LALK, Ulrike LINDEQUIST |
Institute of Pharmacy, Ernst-Moritz-Arndt-University, Friedrich-Ludwig-Jahn-Straße 17, 17487 Greifswald, Germany |
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Abstract Two farnesylhydroquinones were isolated from the fruiting bodies of Ganoderma pfeifferi, farnesylhydroquinone (1) and the new compound ganomycin K (2), (5S)-3-[(E)-7,8-dihydroxy-4,8-dimethylnon-3-enyl]-5-(2,5-dihydroxyphenyl)-furan-2(5H)-one. The structures of 1 and 2 were determined on the basis of mass spectrometric and NMR spectroscopic evidence. The antibacterial activity of the isolated compounds was neglectable.
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Keywords
Ganoderma pfeifferi
farnesylhydroquinone
ganomycin
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Fund:We thank K. Weisz for recording the NMR spectra. Financial support by the federal state of MecklenburgVorpommern and the EU ("Landesforschungsschwerpunkt" EMAU 02 015 20) is gratefully acknowledged. |
Issue Date: 11 February 2018
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