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New Dimeric and seco-Abietane Diterpenoids from Salvia wardii |
| Qiu-Li Xiao1, Fan Xia1, Xing-Wei Yang2, Yang Liao2, Li-Xin Yang2, Yu-Kun Wei3, Xian Li1, Gang Xu2 |
1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming 650500, Yunnan, People's Republic of China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3. Shanghai Chenshan Plant Science Research Center, Chinese Academy of Sciences, Beijing, People's Republic of China |
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Abstract Two dimeric abietane diterpenoids, salviwardins A and B(1 and 2), and a seco-abietane diterpenoid salviwardin C(3), along with five known analogues(4-8), were isolated from the roots of Salvia wardii. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested.
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| Keywords
Salvia wardii
Dimeric abietane diterpenoids
seco-abietane
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| Fund:The work was financially supported by the foundations from NSFC(81373291), the National Science and Technology Support Program of China(2013BAI11B02), the Young Academic Leader Raising Foundation of Yunnan Province(No. 2009CI073), and the foundation from CAS to Dr. G. Xu. |
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Issue Date: 11 February 2018
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